Antimicrobial sensitivity and resistance pattern of Bacteria in hospitalized patients with Urinary Tract Infections (UTI)

Volume 3, Issue 1, February 2019     |     PP. 1-8      |     PDF (529 K)    |     Pub. Date: June 4, 2019
DOI:    308 Downloads     7453 Views  

Author(s)

Amanullah Abbasi, MBBS. FCPS (Urology), Associate Professor CMC/SMBBMU Larkana Pakistan
Aamir Ali Shaikh, MBBS. FCPS (Urology), Consultant Urologist, CMC/SMBBMU Larkana Pakistan
Safiullah Sohu, MBBS. FCPS (Urology), Senior Registrar, CMC/SMBBMU Larkana Pakistan
Mohammad Imran Soomro, MBBS. FCPS (Urology), Consultant Urologist, CMC/SMBBMU Larkana Pakistan
Nisar Ahmed Shaikh, MBBS. M.S (Urology), Associate professor, CMC/SMBBMU Larkana Pakistan
Malik Hussain Jalbani, Professor of Urology, CMC/SMBBMU LARKANA PAKISTAN

Abstract
AbstractIntroduction: Urinary tract infection (UTI) is the 1st most common disease in indoor and outdoor patient presenting in urological practice. Aim of our study to assess, the adequacy of the empirical therapy and resistance pattern of bacteria responsible for UTI admitted in Urology Department.Methodology: This is descriptive cross sectional study in which urine samples collected for urine culture & sensitivity from the patients at Urology department CMCTH/SMBBMU Larkana during period of December 2015 to November 2016. Urine culture & sensitivity with bacterial count of 105 CFU/mL and more bacteria were considered positive and all samples were evaluated for sensitivity and resistance pattern of antimicrobial drugs.Results: 150 samples analyzed in which male patients was 103(68.66%) and female patients were 47(31.33%) with male to female ratio 2:1 with mean age 38.34 years SD±7.8. Among all urinary bacterial infections Escherichia coli was the most common organism seen 89(59.33%) patients followed by Klebsiella pneumoniae, Pseudomonas aeruginosa, Staphylococcus aureus, Proteus mirabilis, mixed organism and enterococcus species. Sensitivity pattern of uro-pathogen were excellent in Meropenem, Tazobactam/Piperacillin, Maxipime, Nitrofurantoin, Fosfomycin, Amikacin and Amoxicillin/clavulanic acid. Resistance pattern was seen in cephalosporin, Penicillin, gentamycin and quinolone.Conclusions: As resistance pattern of organism increasing day by day which increasing morbidity and mortality rate so we recommended urine C/S for all patients admitted in urology ward waiting for urological intervention.

Keywords
UTI, Uro-pathogens, Antimicrobial sensitivity and Resistance pattern

Cite this paper
Amanullah Abbasi, Aamir Ali Shaikh, Safiullah Sohu, Mohammad Imran Soomro, Nisar Ahmed Shaikh, Malik Hussain Jalbani, Antimicrobial sensitivity and resistance pattern of Bacteria in hospitalized patients with Urinary Tract Infections (UTI) , SCIREA Journal of Medicine. Volume 3, Issue 1, February 2019 | PP. 1-8.

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