Purification Propionic Acid using n-Butanol in Semi Batch Reactive Distillation

Volume 6, Issue 1, February 2024     |     PP. 1-19      |     PDF (3440 K)    |     Pub. Date: January 16, 2024
DOI: 10.54647/chemical530047    12 Downloads     36244 Views  


Ahmed Hashim Raza, Department of Chemical Engineering, University College of Technology, Osmania University, Hyderabad-500007, Telangana, India
Sunitha P, Department of Chemical Engineering, University College of Technology, Osmania University, Hyderabad-500007, Telangana, India
Basava Rao V V, Department of Chemical Engineering, University College of Technology, Osmania University, Hyderabad-500007, Telangana, India

Reactive distillation is a cost-effective chemical engineering process intensification method which involves the reaction and separation simultaneously in a single unit. Previously, Propionic Acid has been purified using n-Butanol as an entrainer in a batch setup using reactive distillation in the presence of a cation exchange resin catalyst called Amberlite. The final product is n-Butayl Propionate and it can be subjected to reversible reaction to get pure propionic acid. The extension of reactive distillation in a semi-batch setup to purify Propionic Acid is yet to be studied. In the present work, the Propionic Acid is purified using n-Butanol (nB) as an entrainer through the esterification process to occur in a semi batch reactive distillation unit. The flow rate effect along with the concentration of acid at different weight percentages of catalyst are carried out. As nB possesses the lightest weight in the mixture, it volatilizes to the topmost section of the distillation column during the operation. By means of distillate, it can be eliminated from the reactive system in a typical setup of conventional batch reactive distillation (CBRD) column following which the conversion of PA gets inhibited. Hence, through the approach of semi-batch reactive distillation (SBRD) the purity of acid is verified. Contrarily in the reactive mixture, as water is the second lightest component, it vaporizes to the top of the column and can be separated from the distillate that is being collected. Also, for the products, the reasons that the broad variability in their boiling points obtained after the reaction along with the reduced water content in the reboiler, constrain the occurrence of backward reactions hence, it can be neglected as a factor.

Reactive Distillation, Propionic Acid, n-Butanol, Amberlite, Esterification, n-Butyla Propionate

Cite this paper
Ahmed Hashim Raza, Sunitha P, Basava Rao V V, Purification Propionic Acid using n-Butanol in Semi Batch Reactive Distillation , SCIREA Journal of Chemical Engineering. Volume 6, Issue 1, February 2024 | PP. 1-19. 10.54647/chemical530047


[ 1 ] Dhia Y. Aqar, Ammar S. Abbas, Raj Patel, Iqbal M. Mujtaba, Optimisation of semi-batch reactive distillation column for the synthesis of methyl palmitate, Separation and Purification Technology, 2021, Volume 270, 118776
[ 2 ] Dhia Y. Aqar, Iqbal M. Mujtaba, Economic feasibility of an integrated semi-batch reactive distillation operation for the production of methyl decanoate, Separation and Purification Technology, 2020, Volume 257, 559-566
[ 3 ] Suputtharagris Akkaravathasinp, Phavanee Narataruksa, Chaiwat Prapainainar, The Effect of Feed Location of a Semi-00Batch Reactive Distillation via Esterification Reaction of Acetic Acid and Methanol: Simulation Study, Energy Procedia, 2015, 79, 778–783
[ 4 ] C. Prapainainar, C. Yotkamchonkun, S. Panjatharakul, T. Ratana, S. Seeyangnok, P. Narataruksa, Esterification of acetic acid via semi-batch reactive distillation for pyrolysis oil upgrading: experimental approach, Elsevier Energy Procedia, 2014, 52, 559 – 566
[ 5 ] Wei Qi and Michael F. Malone, Semibatch Reactive Distillation for Isopropyl Acetate Synthesis, Industrial & Engineering Chemistry Research, 2011, 50(3), 1272–1277
[ 6 ] Jonghyun Park, Youngmin Jeong, Myungwan Han, Process intensification of reactive distillation using improved RCMs: Acetic acid production, Chemical Engineering and Processing - Process Intensification, 2020, 157
[ 7 ] E. V. Lupachev, A. V. Polkovnichenko, S. Ya. Kvashnina , V. A. Lotkhova , and N. N. Kulova, Batch Reactive Distillation in Bromodifluoroacetic Acid Synthesis Technology, Theoretical Foundations of Chemical Engineering, 2019, 51(1), 1-12
[ 8 ] Raju. Kalakuntala, R. Navya, T. Sisira, V. V. Basava Rao, Srinath.Surnani, Experimental studies on reactive distillation of propionic acid using n-butanol as entrainer, International Journal of Engineering & Technology, 2018, 7 (3.29) 46-48
[ 9 ] Dhia Y. Aqar, Nejat Rahmanian, Iqbal M. Mujtaba, Feasibility of Integrated Batch Reactive Distillation Columns for the Optimal Synthesis of Ethyl Benzoate, Chemical Engineering and Processing: Process Intensification, 2017, 122, 10-20
[ 10 ] Dhia Y. Aqar, Nejat Rahmanian, and Iqbal M. Mujtaba, Synthesis of Methyl Decanoate Using Different Types of Batch Reactive Distillation Systems, Industrial & Engineering Chemistry Research, 2017, 56(14), 3969–3982
[ 11 ] Dhia Y. Aqar, Nejat Rahmanian, Iqbal M. Mujtaba, Integrated Batch Reactive Distillation Column Configurations for Optimal Synthesis of Methyl Lactate, Chemical Engineering and Processing: Process Intensification, 2016, 108, 197–211.
[ 12 ] Andrea Komesu, Patrícia Fazzio Martins Martinez, Betânia Hoss Lunelli, Rubens Maciel Filho, Maria Regina Wolf Maciel, Lactic acid purification by reactive distillation system using design of experiments, Chemical Engineering and Processing: Process Intensification, 2015, 95, 26–30.
[ 13 ] V. V. Basava Rao, P. Shiva Kumar, Ch. Sailu, S. Ram Mohan Rao, Recovery of Lactic acid by Reactive Distillation, Journal of Applied Sciences, 2014, 14(12); 1289-1293
[ 14 ] Hongxing Wang, Xiangwei Bu, Zhixian Huang, Jinbei Yang, and Ting Qiu, Synthesis of Methacrylic Anhydride by Batch Reactive Distillation: Reaction Kinetics and Process, Ind. Eng. Chem. Res. 2014, 53(44), 17317−17324
[ 15 ] Isabel Figueroa, Shankar Vaidyaraman, and Shekhar Viswanath, Model-Based Scale-up and Design Space Determination for a Batch Reactive Distillation with a Dean−Stark Trap, Organic Process Research & Development, 2013, 17(10), 1300–1310.
[ 16 ] Tian Hui, Huang Zhixian, Qiu Ting, Wang Xiaoda and Wu Yanxiang, Reactive Distillation for Producing n-Butyl Acetate: Experiment and Simulation, Chinese Journal of Chemical Engineering, 2012, 20(5) 980-987
[ 17 ] E.A. Edreder, I.M. Mujtaba, M. Emtir, Optimal operation of different types of batch reactive distillation columns used for hydrolysis of methyl lactate to lactic acid, Chemical Engineering Journal, 2011, 172(1), 467–475.
[ 18 ] Elmahboub A. Edreder, Iqbal M. Mujtaba, Mansour Emtir, Optimization of batch reactive distillation process: Production of lactic acid, Computer Aided Chemical Engineering, 2010, 28:1793-1798
[ 19 ] Rakesh Kumar, Sanjay M Mahajani, Hemant Nanavati and Santosh B Noronha, Recovery of lactic acid by batch reactive distillation, Journal of Chemical Technology and Biotechnology, 2006, 81(7) 1141–1150
[ 20 ] Zhe Guo, Mudassir Ghufran, and Jae W. Lee, Feasible Products in Batch Reactive Distillation, AIChE Journal, 2003, 49(12), 3161-3172
[ 21 ] Sven Steinigeweg and Jurgen Gmehling, n-Butyl Acetate Synthesis via Reactive Distillation: Thermodynamic Aspects, Reaction Kinetics, Pilot-Plant Experiments, and Simulation Studies, Ind. Eng. Chem. Res. 2002, 41(22), 5483-5490
[ 22 ] Sagar B. Gadewar, Michael F. Malone, and Michael F. Doherty, Selectivity Targets for Batch Reactive Distillation, Ind. Eng. Chem. Res. 2000, 39, 1565-1575
[ 23 ] Ganesh Venimadhavan, Michael F. Malone, and Michael F. Doherty, A Novel Distillate Policy for Batch Reactive Distillation with Application to the Production of Butyl Acetate, Ind. Eng. Chem. Res. 1999, 38, 714-722